Developing a new PET myocardial perfusion tracer
نویسندگان
چکیده
منابع مشابه
Clinical myocardial perfusion PET/CT.
The field of nuclear cardiology is witnessing growing interest in the use of cardiac PET for the evaluation of patients with coronary artery disease (CAD). The available evidence suggests that myocardial perfusion PET provides an accurate means for diagnosing obstructive CAD, which appears superior to SPECT especially in the obese and in those undergoing pharmacologic stress. The ability to rec...
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Positron emission tomography (PET) plays an important role in the assessment of myocardial blood flow (MBF). Absolute quantification of MBF is feasible using tracer kinetic models. The most common method for quantifying MBF involves the acquisition of dynamic images with the cyclotron-produced radiopharmaceuticals N-ammonia and O-water. An alternative method is the use of the generator produced...
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Different software tools for quantification of myocardial perfusion SPECT (MPS) studies are routinely used. Several perfusion parameters can be computed automatically. Interpretation of the MPS should start with visual inspection of the rotating planar images, visual analysis of reconstructed SPECT slices and then quantitative analysis to confirm the visual impression. Quantification should be...
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Coronary artery disease is the leading cause of death in the Western world. It is estimated that nearly 7 million people are living with coronary artery disease (CAD) in the United States and about half a million people die from it each year. The most common form of CAD leads to narrowing of the coronary arteries (stenosis) resulting in reduced blood flow and oxygen supplied to the heart muscle...
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Background—Positron-emission tomography (PET) tracers for myocardial perfusion are commonly labeled with short-lived isotopes that limit their widespread clinical use. F-BMS-747158-02 (F-BMS) is a novel pyridaben derivative that was evaluated for assessment of myocardial perfusion by comparison with N-ammonia (NH3) and with radioactive microspheres in a pig model. Methods and Results—Fourteen p...
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ژورنال
عنوان ژورنال: Journal of Nuclear Cardiology
سال: 2009
ISSN: 1071-3581,1532-6551
DOI: 10.1007/s12350-009-9113-x